Cultivation substrate for cardiac myocyte alignment
This is a substrate that easily aligns cultured cardiac muscle cells. It facilitates the fabrication of anisotropic cardiac muscle sheets.
By aligning cultured cardiomyocytes, a sheet can be constructed that reproduces anisotropic excitation propagation similar to cardiac tissue. Anisotropic cardiomyocyte sheets are electrically stable and have a low incidence of reentry. The incidence of reentry induced by drug action in anisotropic cardiomyocyte sheets shows a high correlation with clinical data. The quantification of "drug-induced arrhythmogenic effects," which was difficult with existing testing methods, becomes possible with anisotropic cardiomyocyte sheets. References: Biomaterials 34, 8878–8886 (2013) DOI: 10.1016/j.biomaterials.2013.07.039 Adv Mater. 2017 Jan;29(1) DOI: 10.1002/adma.201602448
- 企業：ブレインビジョン 本社
- 価格：Less than 10,000 yen
